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SARS-CoV-2 pneumonia-receptor binding and lung immunopathology: a narrative review.
Menezes, Maria Clara Saad; Pestana, Diego Vinicius Santinelli; Gameiro, Gustavo Rosa; da Silva, Luiz Fernando Ferraz; Baron, Elodie; Rouby, Jean-Jacques; Auler, José Otavio Costa.
Crit Care ; 25(1): 53, 2021 02 08.
Article in English | MEDLINE | ID: covidwho-1069578

ABSTRACT

The current pandemic of COVID-19 caused thousands of deaths and healthcare professionals struggle to properly manage infected patients. This review summarizes information about SARS-CoV-2 receptor binding dynamics and intricacies, lung autopsy findings, immune response patterns, evidence-based explanations for the immune response, and COVID-19-associated hypercoagulability.


Subject(s)
COVID-19/physiopathology , Carrier Proteins/physiology , Lung Diseases/physiopathology , Pneumonia, Viral/physiopathology , SARS-CoV-2/pathogenicity , COVID-19/immunology , Carrier Proteins/immunology , Humans , Lung Diseases/immunology , Pandemics , Pneumonia, Viral/immunology , SARS-CoV-2/immunology
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